The genus Nandopsis contains a number of larger, aggressive cichlids. The Mayan Cichlid is a large eating machine, and will gulp down any prey items which can fit into its mouth. They can be rather aggressive with each other and with other fishes.

Care should be taken to avoid placing these fish with smaller tank mates, as these are apt to be eaten. They will generally mix well with ohter non cichlids, provided these fish are of good size and fairly active. Large rainbowfish, barbs, and the like are all good choices. Similarly aggessive cichlids may be mixed with these fish, with caution.